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Fig. 5 | Molecular Medicine

Fig. 5

From: Exploring proteomic immunoprofiles: common neurological and immunological pathways in multiple sclerosis and type 1 diabetes mellitus

Fig. 5

Functional analysis comparison between T1DM and MS. A The chart shows the correlations between the DEPs in patients with T1DM and MS (compared to Healthy controls) and different canonical pathways, according to Ingenuity functional assays: IP immunological pathways, NP neurological pathways, CTP cellular trafficking pathways, SP signaling pathways, MP metabolic pathways, CP cardiovascular pathways, AD Autoimmune diseases, KP kidney pathways. B The chart shows the correlations between the number of DEPs in T1DM and MS and the disease and functions found by ingenuity: SF signaling functions, IIR immune or inflammatory response, ND neurological disease, CD cardiovascular disease, MT membrane trafficking, RF renal function, LM lipid metabolism. C Common canonical pathways identified for T1DM and MS. Pathways with more than two significant proteins are represented. D Common disease and function annotation between patients with T1DM and MS. Pathways with more than two significant proteins are shown

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Molecular Medicine

ISSN: 1528-3658