Table 2 Functional classification of protein changes related with neurological system

T1DM

Dysmyelination

3,90E-05

ARHGEF6↓, CNP↓, NADK2↓, PSAP↑, SLC25A12↓

5

Leukodystrophy

2,28E-04

ARHGEF6↓, CNP↓, NADK2↓, PSAP↑

4

Abnormal brain myelination

1,28E-03

CNP↓, PSAP↑, SLC25A12↓

3

Hereditary myelin disorder

1,61E-03

ARHGEF6↓, NADK2↓, PSAP↑

3

Hypomyelination of brain

6,41E-03

CNP↓, SLC25A12↓

2

Alzheimer disease

6,85E-03

APOA2↓, APOC1↓, APOC3↓, C1R↓, CNP↓, GLRX↓, GSK3B↓, PON1↓, PSAP↑, SELENBP1↓

10

Quantity of Ca2 + 

2,16E-02

APOC3↓, CD59↑, F2RL3↑, ITPR1↓

4

Outgrowth of neurites

3,60E-02

GSK3B↓, PSAP↑

2

Movement Disorders

4,67E-02

AP1S1↓, ARHGEF7↓, CNP↓, CSTB↓, CYTH1↑, GSK3B↓, ITPR1↓, PON1↓, PSAP↑, SEC11A↓, STMN1↓

11

MS

Quantity of Ca2 + 

2,01E-02

CD59↑, CXCR4↑, ORM1↑

3

Formation of focal adhesions

2,25E-02

SLC9A1, STMN1↓

2