Fig. 1
From: CYFIP1 coordinate with RNMT to induce osteosarcoma cuproptosis via AURKAIP1 m7G modification
CYFIP1 expression in osteosarcoma and its relationship to patient survival. A, B. Low CYFIP1 expression was detected in OS tissues while high CYFIP1 expression in their adjacent tissues. C. IHC staining showed the representative images of low or high expression of CYFIP1. D. Kaplan-Meier survival curve exhibited that low CYFIP1 expression was associated with the worse survival statuses in Xiangya hospital (Log-rank p = 0.0011, HR = 0.377, n[high] = 42, n[low] = 48 ). E. Kaplan-Meier survival curve exhibited that low CYFIP1 expression was associated with the worse survival statuses in TARGET-OS cohort (Log-rank p = 0.0006, HR = 0.261, n = 42 per group). The data represent the mean ± S.D. *P < 0.05 or **P < 0.01 indicates a significant difference between the indicated groups