Fig. 6
From: CYFIP1 coordinate with RNMT to induce osteosarcoma cuproptosis via AURKAIP1 m7G modification
CYFIP1 coordinated with RNMT to facilitate the m7G modification of their targets. A, B. RIP and m7G-RIP sequencing. C. The intersected genes between mRNA, RIP and m7G-RIP sequencing. D-I. RIP- and m7G-RIP-qPCR identified AURKAIP1, PYRC1 and TK1 as the targets of CYFIP1-RNMT complexes. J, K. Gene set enrichment analysis of mRNA sequencing. L, M. The RNA stability assays of AURKAIP1. N. Overexpression of CYFIP1 increased the expression of AURKAIP1. The data represent the mean ± S.D. *P < 0.05, **P < 0.01, and ***P < 0.0001 indicates a significant difference between the indicated groups