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Table 1 Average neutralization activity of BP2-MSC culture supernatants compared with that of wtMSC culture supernatants

From: An engineered miniACE2 protein secreted by mesenchymal stromal cells effectively neutralizes multiple SARS-CoV- 2 variants in vitro

SARS-CoV- 2 variant → 

Neutralization average

Wuhan

Mu

BA.1

BA.2

RBD/Supernatant ratio

RBD/Supernatant ratio

RBD/Supernatant ratio

RBD/Supernatant ratio

Donor ↓

4:2

4:3

4:2

4:3

4:2

4:3

4:2

4:3

wtMSC0915

1.70

2.67

2.25

1.72

23.96

18.40

3.61

4.24

BP2-MSC0915

45.51

60.20

44.92

63.67

10.62

34.28

35.06

49.17

wtMSC0923

2.25

1.56

2.35

2.16

9.17

15.05

9.74

5.94

BP2-MSC0923

45.98

65.27

38.48

50.87

18.52

40.00

39.45

54.13

wtMSC0996

5.37

3.65

1.22

2.19

15.94

15.55

3.64

4.64

BP2-MSC0996

18.69

32.19

21.73

38.48

18.99

28.13

27.97

34.18

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Molecular Medicine

ISSN: 1528-3658