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Fig. 3 | Molecular Medicine

Fig. 3

From: Transcriptome-wide analysis reveals potential roles of CFD and ANGPTL4 in fibroblasts regulating B cell lineage for extracellular matrix-driven clustering and novel avenues for immunotherapy in breast cancer

Fig. 3

WGCNA analysis associated with the ECM clusters. A Heatmap plotting the results of WGCNA analysis based on ECM components- and regulators-related gene expression data identified gene modules with high covariance. B Heatmap plotting the module-trait relationships. C Dot plot demonstrating the correlation between module membership and gene significance in blue, turquoise, and brown module. D Cytoscape illustrating the relative expression level, PPI network, and enriched Reactome pathway of module genes. E Venn diagrams showing the intersection of specific upregulated and downregulated DEGs of each ECM cluster with module genes

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Molecular Medicine

ISSN: 1528-3658