Fig. 4
From: Endogenous Galectin-8 protects against Th17 infiltration and fibrosis following acute kidney injury
Cortical damage and fibrosis are increased during the fibrotic phase in Lgals8−/− mice. A PAS, Masson´s Trichrome and Sirius Red staining in representative images of kidney sections from Lgals8+/+ and Lgals8−/− mice 14 days after damage induction. Scale bar: 100 μm. B Renal cortical damage measurements show the extent of the injured area in Lgals8+/+ and Lgals8−/− mice. C Fibrotic area quantified by collagen stained blue in kidney sections from Lgals8+/+ and Lgals8−/− mice. D Collagen-positive area was quantified by collagen stained red in kidney sections. E Immunoblot quantification of fibronectin-1 in the kidney of Lgals8+/+ and Lgals8−/− mice normalized to GAPDH. Data represent mean ± SEM of n = 4–6, *p < 0.05, **p < 0.01, ***p < 0.001